INTERNATIONAL MASTER IN MATERNAL-FETAL MEDICINE
The first Placenta paper in Chapter 3, demonstrated significantly increased mRNA expression of the candidate genes – ACVR1, INHBB, ERAP1, ERAP2, LNPEP, COL4A1 and COL4A2, in the pre-eclamptic maternal decidual tissue, which correlated with greater clinical severity of PE.
Phd Graduates 2016 - UKZN's College of Health Sciences
The incidence of pre-eclampsia and eclampsia was7.0%. Prenatal care and education were not significantly associatedwith pre-eclampsia/eclampsia. Older maternal age at delivery(OR=3.18; 95%CI: 1.31, 7.76) and heavier maternal weight (OR=3.24;95%CI: 1.76, 5.98) measured during prenatal care were bothsignificantly associated with PIH/pre-eclampsia/eclampsia.
The second Placenta paper in Chapter 4, examined the levels of arresten and canstatin fragments, which are derived from the COL4A1 and COL4A2 genes respectively, in the plasma from pre-eclamptic women and gestational age matched normotensive controls.