synthesis of the range of indazoles.

A Versatile Synthesis of 3-Substituted Indazoles Byung Chul Kim; Jin Il Kim; Yurngdong Jahng;

Synthesis of N -Heterocycles - Organic Chemistry Portal

The preparation of further novel indazole derivatives containing different functional groups and substituents was performed by synthesising alternative 1,3- dipole and dipolarophile analogues and provided additionally diverse compounds.

Hydrazine derivative synthesis by C-N coupling

In addition, some common syntheses of indazole compounds are presented as well as a brief discussion on the importance of indazole compounds as therapeutic agents.

Next, the synthetic methods to prepare the indazole compounds are provided followed by discussion on derivatisation of the indazole compounds including N-deacylation, N-benzylation and ester side-chain transformation of some alkene-containing indazoles.