EP0501704A1 - Synthesis of beta-cyanohydrins - Google …

3.2.1 Production levels and processes Acetonitrile is a by-product of acrylonitrile synthesis.

Synthesis of beta -cyanohydrins ..

RECOMMENDATIONS FOR THE PROTECTION OF HUMAN HEALTH a) Acetonitrile and mixtures containing it should be clearly labelled with a warning of the toxicity of acetonitrile.

Cox, R. F. B., Stormont, R. T. 2003. Acetone Cyanohydrin. Organic Syntheses. 1.

A safe production method for acetone cyanohydrin

Urinary acetonitrile was detectable for 4 days after dosing, whereas free and combined cyanide were detectable until 11 days, at which time the animals were sacrificed.

Acetonitrile is also used in biotechnology research as a solvent in the synthesis of DNA and peptide sequencing (Borman, 1990).

b) Comparative studies on the kinetics of cyanide formation from acetonitrile, as well as of conjugation to thiocyanate and its elimination, should be conducted.


Acetonitrile (EHC 154, 1993) - IPCS INCHEM

Main use patterns of acetonitrilea Extraction of fatty acids and animal and vegetable oils Extraction of unsaturated petroleum hydrocarbons Solvent for polymer spinning and casting Moulding of plastics Removal of tars, phenols and colouring matter from petroleum hydrocarbons Purification of wool resin Recrystallization of steroids Starting material for synthesis of chemicals Solvent in DNA synthesis and peptide sequencing Medium for promoting reactions Solvent in non-aqueous titrations Non-aqueous solvent for inorganic salts High-pressure liquid chromatographic analysis Catalyst and component of transition-metal complex catalysts Extraction and refining of copper Stabilizer for chlorinated solvents Perfume manufacture Pharmaceutical solvents a From: Veatch et al.

nerol 106-25-2 - The Good Scents Company

Acetonitrile is also used as a starting material for the synthesis of many chemicals such as acetophenone, alpha-naphthyl acetic acid, thiamine and acetomidine (Hawley, 1971).

nerol is cis isomer of geraniol; used in perfumery

Laetrile (another name for amygdalin derived from apricot kernels), which was formerly used as an anticancer agent, releases cyanide upon metabolism. Bitter almonds and apricot pits containing cyanogenic glycosides are still sold in health food stores and over the Internet (Suchard et al., 1998). Other drugs, such as sodium nitroprusside, which is used as an antihypertensive and in congestive heart failure (Guiha et al., 1974; Tinker, 1976; Aitken et al., 1977; Schultz, 1984; Rindone & Sloane 1992), also liberate hydrogen cyanide in the body. In sodium nitroprusside, the CN moiety represents 44% by weight of the molecule. Some aliphatic nitriles that are widely used in the chemical industry — i.e., acetonitrile (IPCS, 1993), acrylonitrile (IARC, 1999), succinonitrile, and adiponitrile — also release cyanide upon metabolism (Willhite & Smith, 1981).

of many essential oils including neroli and bergamot oils

Acetonitrile has been used as a solvent for polymer spinning and casting because of the combination of high solubility and desirable intermediate volatility.

(Z)-3-hexen-1-ol, 928-96-1 - The Good Scents Company

IDENTITY, PHYSICAL AND CHEMICAL PROPERTIES, AND ANALYTICAL METHODS Chemical formula: CH3CN Chemical structure: Relative molecular mass: 41.05 CAS chemical name: acetonitrile CAS registry number: Synonyms: cyanomethane, ethanenitrile, nitrile of acetic acid, methyl cyanide, ethyl nitrile, methanecarbonitrile Specifications for commercial acetonitrile are given in Table 1.