2-methyl-3-(methyl thio) pyrazine, 2882-20-4

Other metabolites of MEK, 2-butanol or 2,3-butanediol, which DiVincenzo et al.

methyl 2-methyl-3-furyl disulfide, 65505-17-1

Schulz F, Mueller P, & Kramer D (1981) [Model experiments on the phytotoxic effect of organic constituents in wastewater from lignite refining in soil treatment.] Arch Acker-Pflanzenbau Bodenkd, 25: 745-753 (in German) Schwetz BA, Leong BKJ, & Gehring PJ (1974) Embryo- and fetotoxicity of inhaled carbon tetrachloride, 1,1-dichloroethane and methyl ethyl ketone in rats.

The butanol isomers have different melting and boiling points

Traiger GJ, Bruckner JV, Jiang WD, Dietz FK, & Cooke PH (1989) Effect of 2-butanol and 2-butanone on rat hepatic ultrastructure and drug metabolizing enzyme activity.

Khasanov AA, Isidorov VA, Zenkevich IG, & Ioffee BV (1982) [Gas chromatography/ mass spectrometry study of the composition of volatile emissions from Juniperus serawechanica Kom.] Dokl Akad Nauk Uzb SSR, 12: 29-31 (in Russian).


Methyl ethyl ketone (EHC 143, 1992) - IPCS INCHEM

Since MEK and 2,3-butanediol disappear from blood and urine and there is no evidence for accumulation elsewhere in the body, the above data suggest that the bulk of MEK absorbed by mammals enters the general metabolism and is eliminated from the body as simple compounds like carbon dioxide and water whose source is not readily identifiable.

Alkene Reactions - Michigan State University

In a similar study of workers occupationally exposed to a mixture of solvents, the excretion of MEK and a major recognizable metabolite, 3-hydroxy-2-butanone, was 0.1% of alveolar uptake (Perbellini et al., 1984).

Two isomeric alkene starting materials are available for your use

It is likely that 2-butanol, like ethanol (Mezey, 1976), inhibits oxidative pathways of drug metabolism and thus inhibits the hydroxylation step leading to 3-hydroxy-2-butanone.

Butanol is used in the synthesis of 2-butoxyethanol.

Experimental data and equations derived from this data indicated that the major metabolic pathway is butanol -> MEK -> 3-hydroxy-2-butanone -> 2,3-butanediol, with small or non-existent reverse flows.

2-Methyl-2-butanol(75-85-4) MSDS Melting Point …

MEK has been reported to be a metabolic end product of natural gas (methane 88%, ethane 5%, propane 5%, isobutane 2% with traces of tert-butyl mercaptan and methyl acrylate) inhaled for 2 h by ICR mice (Tsukamoto et al., 1985a).

Flotation agent, organic synthesis

It also has been reported in chicken breast muscle (Grey & Shrimpton, 1967), weed residues (Bradow & Connick, 1988), southern pea seeds (Fisher et al., 1979), insect pheromones (Cammaerts et al., 1978; Attygalle et al., 1983), juniper leaves (Khasanov et al., 1982); marine macroalgae (seaweeds) (Whelan et al., 1982) and as a product of microbial metabolism (Patel et al., 1982; Mohren & Juttner, 1983; Zechman et al., 1986), including cultures isolated from fresh water and soil (Hou et al., 1983; Patel et al., 1983).