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4,536,518 discloses a process for the synthesis of Sertraline hydrochloride
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Improved Industrial Synthesis ..

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Synthesis by precipitation polymerization of a …

Figure 1 shows a flow diagram indicating the relationship between research questions in this CER. The first box in the figure shows the last question (KQ5) where current guidelines are reviewed. The other questions are related to interventions used following the unsatisfactory response to an SSRI for the index episode of depression. The treatment options following a failed response include the eight options (defined as interventions) for KQ1. Harms associated with any of these interventions are evaluated in KQ2 and can include suicide, sexual dysfunction, gastrointestinal effects and neuropsychiatric effects. The study effects are evaluated in KQ1, 3 and 4, with the latter two questions considering subgroups related to different population subgroups and different types of SSRIs. We note that intermediate outcomes, such as response and remission may precede quality of life or societal outcomes (costs, utilization).

Journal of the Brazilian Chemical Society ..
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Product name:
CAS no.:79559-97-0
Molecular Formula: C17H18Cl3N
Molecular Weight:342.69
Appearance: White solid
Product description:For the synthesis of Antidepressant Sertraline Hydrochloride.

Synthesis by precipitation polymerization of a molecularly ..
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