Dehydration Synthesis and Hydrolysis Flashcards | Quizlet

Both glycoside and peptide linkages result from dehydration synthesis. - 735802

Dehydration Synthesis VS Hydrolysis - Bio Molecules

With colchicine (1) in hand, we proceeded to investigate our proposed syntheses of β-lumicolchicine (3) and NCME (2) (). The irradiation of a 10:1 (v/v) CH3CN/acetone solution of 1 (0.0025 mol/L) with a 125 W high-pressure mercury arc lamp surrounded by a Pyrex water jacket for 25 min resulted in β-lumicolchicine (3) with a much improved yield of 68%.

combining two C 6 H 12 O 6 molecules via dehydration synthesis would result in C 12 H ..

Dehydration reaction - Wikipedia

A first synthesis of the peracetyl racemate (25) of hydroxyvalidamine (3), one of the degradation products of antibiotic validamycin B (1), is reported. The present result fully confirmed the proposed structure of 3. The sequence of reactions involves stereospecific peracid oxidation of the protected branched-chain unsaturated cyclitol 18 to give rise to a versatile epoxide (19) and regioselective azidolysis of 19 followed by reduction of the azido group with hydrogen sulfide. In addition, the peracetyl racemate (30) of valienamine (4) has been newly synthesized from the intermediate compound (26) of 3 by dehydration through the mesylate 27, a similar sequence of which may be generally applicable for preparation of other valienamine derivatives.

10/02/2015 · QUICK AND EASY Overview of hydrolysis and dehydration synthesis

N2 - A first synthesis of the peracetyl racemate (25) of hydroxyvalidamine (3), one of the degradation products of antibiotic validamycin B (1), is reported. The present result fully confirmed the proposed structure of 3. The sequence of reactions involves stereospecific peracid oxidation of the protected branched-chain unsaturated cyclitol 18 to give rise to a versatile epoxide (19) and regioselective azidolysis of 19 followed by reduction of the azido group with hydrogen sulfide. In addition, the peracetyl racemate (30) of valienamine (4) has been newly synthesized from the intermediate compound (26) of 3 by dehydration through the mesylate 27, a similar sequence of which may be generally applicable for preparation of other valienamine derivatives.

Which of the following would not be the result of a dehydration synthesis reaction


Calculating dehydration synthesis ..

In summary, we developed a concise and highly enantioselective synthesis of colchicine (>99% ) in eight steps in 9.3% overall yield without the need for protecting groups. An unusual Wacker oxidation was used for enabling the regioselective construction of the highly oxidized tropolone C-ring. β-Lumicolchicine was prepared through a 4π-electrocyclization reaction with a much-improved yield compared with existing procedures, and the allocolchicinoid NCME was synthesized from β-lumicolchicine through a novel decarbonylation/electrocyclic ring-opening cascade reaction.