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4.7.3 Toxicity in humans There have been sporadic reports of poisoning with sodium or potassium salts of chlorate (Temperman & Maes, 1966; Mengele et al., 1969; Yoshida et al., 1977; Bloxham et al., 1979; Helliwell & Nunn, 1979; Steffen & Seitz, 1981).
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Lilly PD, Andersen ME, Ross TM, & Pegram RA (1998) A physiologically based pharmacokinetic description of the oral uptake, tissue dosimetry and rates of metabolism of bromodichloromethane in the male rat.
Kurokawa Y, Takayama S, Konishi Y, Hiasa Y, Asahina S, Takahashi M, Maekawa A, & Hayashi Y (1986b) Long-term in vivo carcinogenicity tests of potassium bromate, sodium hypochlorite, and sodium chlorite conducted in Japan.
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Trichloroacetic acid (trichloroacetate) 18.104.22.168 General toxicological properties and information on dose-response in animals 22.214.171.124 Reproductive effects 126.96.36.199 Developmental effects 188.8.131.52 Neurotoxicity 184.108.40.206 Toxicity in humans 220.127.116.11 Carcinogenicity and mutagenicity 18.104.22.168 Comparative pharmacokinetics and metabolism 22.214.171.124 Mode of action
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Chloral hydrate (trichloroacetaldehyde, chloral) 126.96.36.199 General toxicological properties and information on dose-response in animals 188.8.131.52 Toxicity in humans 184.108.40.206 Carcinogenicity and mutagenicity 220.127.116.11 Comparative metabolism and pharmacokinetics 18.104.22.168 Mode of action
I know the Chlorate is Very dangerous and should ..
Halogenated aldehydes and ketones other than chloral hydrate 22.214.171.124 General toxicological properties and information on dose-response in animals 126.96.36.199 Toxicity in humans 188.8.131.52 Carcinogenicity and mutagenicity 184.108.40.206 Comparative pharmacokinetics and metabolism 220.127.116.11 Mode of action
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intraperitoneal IPCS International Programme on Chemical Safety JECFA Joint FAO/WHO Expert Committee on Food Additives LD50 median lethal dose LDH lactate dehydrogenase LDL low-density lipoprotein LOAEL lowest-observed-adverse-effect level MA 3,4-(dichloro)-5-hydroxy-2(5H)-furanone MBA monobromoacetic acid/monobromoacetate MCA monochloroacetic acid/monochloroacetate MNU methylnitrosourea MOR mortality odds ratio MRI magnetic resonance imaging MTBE methyl tert-butyl ether MX 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone NADP nicotinamide adenine dinucleotide phosphate NOAEL no-observed-adverse-effect level NOEL no-observed-effect level NOM natural organic matter NTP National Toxicology Program (USA) 8-OH-dG 8-hydroxy-2-deoxyguanosine OR odds ratio PAS periodic acid/Schiff's reagent PBPK physiologically based pharmacokinetic model PFBHA O-(2,3,4,5,6-pentafluorobenzyl)-hydroxylamine p Ka log acid dissociation constant PPAR peroxisome proliferator activated receptor PPRE peroxisome proliferator responsive element RR relative risk SCE sister chromatid exchange SD standard deviation SDH sorbitol dehydrogenase SE standard error SGOT serum glutamate-oxaloacetate transaminase SGPT serum glutamate-pyruvate transaminase SMR standardized mortality ratio SSB single strand breaks TBA tribromoacetic acid/tribromoacetate TBARS thiobarbituric acid reactive substances TCA trichloroacetic acid/trichloroacetate TCAN trichloroacetonitrile TCPN trichloropropanone TDI tolerable daily intake TGF transforming growth factor THM trihalomethane TOC total organic carbon TOX total organic halogen TPA 12- O-tetradecanoylphorbol-13-acetate UDS unscheduled DNA synthesis UV ultraviolet UVA254 UV absorbance at 254 nm Vmax maximum rate of metabolism WHO World Health Organization 1.
Chlorate; Sodium Chlorate; Potassium Chlorate; ..
3.2.3 Toxicity in humans The primary harmful effects of chloramine have been documented in humans poisoned by chloramine formed when household bleach was mixed with ammonia for use as a cleaning solution.