DNA Replication & Protein Synthesis - PBS

DNA polymerase proofreading: active site switching catalyzed by the bacteriophage T4 DNA polymerase

DNA replication is the process of ..

DNA replication is the production of identical from a single double-stranded DNA molecule. Each molecule consists of a strand from the original molecule and a newly formed strand. Prior to replication, the uncoils and strands separate. A replication fork is formed which serves as a template for replication. Primers bind to the DNA and DNA polymerases add new nucleotide sequences in the 5′ to 3′ direction. This addition is continuous in the leading strand and fragmented in the lagging strand. Once elongation of the DNA strands is complete, the strands are checked for errors, repairs are made, and telomere sequences are added to the ends of the DNA.

Formation of N-branched oligonucleotides as by-products in solid-phase oligonucleotide synthesis

DNA replication occurs in the S phase ..


S phase - The second, middle part of interphase, occurring between G1 and G2; during S phase DNA is duplicated before division.

This describes S phase control in fission yeast, and provides links to ...

Damage to DNA after S phase (the G2 checkpoint), inhibits the of Cdk1 ...

Chromosomal DNA replication occurs during a phase of the cell ..

The lagging strand begins replication by binding with multiple primers. Each primer is only several bases apart. DNA polymerase then adds pieces of DNA, called Okazaki fragments, to the strand between primers. This process of replication is discontinuous as the newly created fragments are disjointed.

The phase of the mitotic cycle during which DNA synthesis occurs

It says, as described in relation to laser illumination of a DNA sample, that such illumination can be expected to turn the DNA into a series of active adaptive phase conjugate mirrors (see figure below)/holographic transducers (see figure of laboratory illustration earlier), from which would resonantly emerge a beam of radiation, on which is carried the holographic information as encoded in the DNA.

DNA synthesis only occurs during the S phase of ..

Enzymes known as DNA polymerases are responsible creating the new strand by a process called elongation. There are five different known types of DNA polymerases in and . In bacteria such as , polymerase III is the main replication enzyme, while polymerase I, II, IV and V are responsible for error checking and repair. DNA polymerase III binds to the strand at the site of the primer and begins adding new base pairs complementary to the strand during replication. In , polymerases alpha, delta, and epsilon are the primary polymerases involved in DNA replication. Because replication proceeds in the 5' to 3' direction on the leading strand, the newly formed strand is continuous.

DNA Replication and Protein Synthesis - PBS

Such a state vector description (with gauge invariant phases) by means of which each DNA molecule can clearly be expected to be described, would explain the difference between the nature of quantum interference and quantum self interference, which DNA from its double helical structure can thus be recognized to concern.

A Science Odyssey: You Try It: DNA Workshop - PBS

The leading strand is the simplest to replicate. Once the DNA strands have been separated, a short piece of called a primer binds to the 3' end of the strand. The primer always binds as the starting point for replication. Primers are generated by the enzyme DNA primase.