Synthesis of Radiolabeled Compounds

Alkane synthesis by C-C coupling - Organic Chemistry Portal

Thieme E-Books & E-Journals - Synthesis / Issue

By far the greatest use of butadiene is in the manufacture of co-polymers produced from phenylethene (styrene) and butadiene, and propenonitrile (acrylonitrile), butadiene and phenylethene (styrene), . The next biggest use is in the manufacture of poly(butadiene), a synthetic rubber, which is principally used as one of the components in the rubber used for car tyres:

Alkene Reactivity - Michigan State University

Other synthetic rubbers made from butadiene include neoprene which is poly(2-chlorobuta-1,3-diene), often known as polychloroprene. Chloroprene is made from butadiene, by first reacting it with chlorine in the gas phase at ca 500 K to form 3,4-dichlorobut-1-ene and 1,4-dichlorobut-2-ene. The former, on reaction with sodium hydroxide, yields chloroprene:

Another synthetic made from butadiene is NBR (Nitrile Butadiene Rubber), the other monomer being . NBR's ability to withstand a range of temperatures from 220 to 380 K allows it be used in several important aeronautical applications, for example to make fuel and oil handling hoses and seals, where ordinary rubbers cannot be used. It is also used to make protective gloves for use in the nuclear industry. NBR is also used in everyday items, for example in footwear.